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Favipiravir—a prophylactic treatment for Ebola contacts?

THE LANCET byMichel Van Herp, Hilde Declerck and Tom Decroo June 13, 2015

.. the efficacy of candidate Ebola vaccines for primary prevention has not been proven.2 Furthermore, in communities in which Ebola transmission might be ongoing, an important question is: how will such a vaccination be perceived if a vaccinated person develops Ebola? Such a scenario is possible in people who contract Ebola virus before vaccination. If a person is infected with Ebola virus before vaccination, the vaccine might have a post-exposure prophylactic effect. However, how effective this prophylaxis might be is unknown.2 Moreover, if someone is infected more than 48 h before vaccination, the post-exposure prophylactic effect is likely to be insufficient, leading to possible development of Ebola after vaccination. This scenario is likely to result in serious issues relating to community trust and acceptance of an Ebola vaccine.3 How to exclude Ebola among people presenting with post-vaccination fever is also an issue.2

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Japanese Ebola test gives results in 11 minutes: researcher

AFP     April  9, 2015

Tokyo  A Japanese research team said on Thursday it had developed a field test for Ebola that gives results in just over 11 minutes -- down from the 90-minute test used now.

The breakthrough by Nagasaki University's Institute of Tropical Medicine will allow medics to move much more quickly in treating people with the haemorrhagic fever, Professor Jiro Yasuda told AFP.

"The result time was unexpectedly short," said Yasuda of the trial conducted in Guinea last month on 100 samples, of which 47 proved positive.

The Guinean government has now asked the institute and its collaboration partner Toshiba to supply equipment to roll out the test, he added.

Read complete story.
http://news.yahoo.com/japanese-ebola-test-gives-results-11-minutes-researcher-064839139.html

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Fujifilm says tests results on Avigan as Ebola drug by end-2014

REUTERS                                                 Nov. 11, 2014
By Ayai Tomisawa and Reiji Murai

TOKYO--Fujifilm Holdings Corp said it expects its influenza drug Avigan to be approved by international government bodies to treat Ebola after it receives clinical test results as early as the end of the year.

Tablets of Avigan (generic name : Favipiravir), a drug approved as an anti-influenza drug in Japan and developed by drug maker Toyama Chemical Co, a subsidiary of Fujifilm Holdings Co. are displayed during a photo opportunity at Fujifilm's headquarters in Tokyo October 22, 2014. Credit: Reuters/Issei Kato

Fujifilm has been growing its pharmaceutical division through a series of mergers and acquisitions as its photography business wanes. In 2008, it bought Toyama Chemical Co, whose drug Avigan has been drafted to the global fight against Ebola.

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