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Brazil scales back efficacy claims for COVID-19 vaccine from China

In the third in a series of conflicting announcements about a Chinese-made COVID-19 vaccine candidate, Brazilian researchers reported today that the results of their efficacy trial were less impressive than they claimed last week. When analyzed by stricter criteria than used earlier, the vaccine’s efficacy against all forms of COVID-19, including mild cases, dropped from about 78% to 50%.

The vaccine still appeared to give nearly 100% protection against disease severe enough to require hospitalization, although the trial amassed too few of those cases for that result to reach statistical significance.

Commenting at the press conference today, microbiologist Natália Pasternak Taschner, president of the Question of Science Institute, a Brazilian nonprofit that aims to support public policy based on scientific evidence, said it was a “clear and clean study” and stressed that she wants th vaccine for herself and her parents. “We do not need to say this is the best vaccine in the world,” said Pasternak, who was not involved with the trial. “We have to say that this is our vaccine and it is a good vaccine to start the process of pandemic control.”

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OVERVIEW: International COVID-19 developments

(Reuters) - Britain saw record-high COVID-19 deaths and Spain posted its biggest one-day jump in cases since October, while the head of the World Health Organization said there was a “clear problem” of low- and middle-income countries not yet receiving vaccine supplies.

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Canada will require incoming international air passengers to test negative before boarding, and other news from around the world

https://www.nytimes.com/live/2021/01/02/world/covid-19-coronavirus#canada-will-require-incoming-international-air-passengers-to-test-negative-before-boarding-and-other-news-from-around-the-world

Canada will require passengers seeking to board international flights into the country to show their airline proof of a negative coronavirus test, in addition to entering an already existing, mandatory 14-day quarantine on arrival.

The new rule, which the government announced on Thursday, will take effect on Jan. 7 and will require proof of a negative PCR test taken in the previous 72 hours. PCR tests must be sent to a lab and can take several days to process, unlike the rapid antigen test, which gives a result in about 30 minutes.

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A side-by-side comparison of the Pfizer/BioNTech and Moderna vaccines

In an ideal world, a pandemic vaccine could be delivered in a single shot, so supplies could be stretched to cover a lot of people. It would trigger no side effect more significant than a sore arm. And it would be easy to ship and store.

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What the data say about border closures and COVID spread

As countries in Europe rush to close their borders to the United Kingdom to prevent transmission of a new — and potentially more transmissible — variant of SARS-CoV-2, research has estimated the effect of international travel restrictions on COVID-19 spread earlier in the pandemic.

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