https://medicalxpress.com/news/2024-04-broadly-coronavirus-vaccine.html#google_vignette

Researchers develop more broadly protective coronavirus vaccine

Scientists have been searching for the optimal coronavirus vaccine since the COVID-19 pandemic started. The mRNA vaccines developed through the federal government's "Operation Warp Speed" program were a massive innovation; however, annually updating those boosters for specific SARS-CoV-2 variants is inefficient for scientists and patients.

SARS-CoV-2 is just one member of the Sarbecovirus (SARS Betacoronavirus) subfamily (others include SARS-CoV-1, which caused the 2002 SARS outbreak, as well as other viruses circulating in bats that could cause future pandemics).

Mpox vaccine boosters necessary to restore faded protection, study shows - UPI.com Vaccine protection against mpox fades quickly in the human immune system, even in people who've received the full two-dose regimen, a new real-world study shows. UPI

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Antibody levels fell to low or near zero within the first few months of getting the vaccine, unless the person had previously received a smallpox vaccine, scientists reported Saturday at the European Congress of Clinical Microbiology and Infectious Diseases in Barcelona.