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Moderna combination Covid, flu vaccine moves to final stage trial after positive data

Wed, 2023-10-04 09:26 — mike kraft

Moderna combination Covid, flu vaccine shows positive data (cnbc.com)

 

  • Moderna on Wednesday said its combination vaccine targeting Covid and the flu will move to a final stage trial after showing positive results in an earlier study.
  • The biotech company is hoping its shot, mRNA-1083, can win approval from regulators in 2025. 

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Drug prices: Major drugmakers agree to negotiate drug prices with U.S. government

Tue, 2023-10-03 19:21 — mike kraft
Drugmakers agree to negotiate drug prices with government, White House says The manufacturers of 10 prescription drugs — including Eliquis, Xarelto and Januvia — will take part in the negotiations. NBC News

Major drug companies including Johnson & Johnson, Merck and Bristol Myers Squibb have committed to participate in Medicare drug price negotiations with the federal government, the Biden administration said Tuesday.

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Survey indicates resistance to COVID booster shots affected by prior infections, fear of side effects and doubts about usefullness

Tue, 2023-10-03 18:59 — mike kraft
COVID booster uptake hindered by prior infections, fear of side effects Ratana21/iStock CIDRAP

Only 20% of Americans eligible for COVID-19 boosters get them, and today in Vaccine, researchers published the results of a new survey of 2,000 US adults to understand why uptake is so low.

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Novavax's updated protein-based Covid-19 vaccine approved by U.S. FDA

Tue, 2023-10-03 18:51 — mike kraft
FDA signs off on updated protein-based Covid-19 vaccine from Novavax | CNN The US Food and Drug Administration on Tuesday authorized Novavax’s updated protein-based Covid-19 vaccine for people 12 and older. Amanda Sealy, Brenda Goodman CNN

This vaccine is effective against EG.5, the currently dominant coronavirus strain in the United States, and like Pfizer and Moderna’s mRNA vaccines, it has been updated to target the XBB Omicron subvariant.

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Britain’s COVID-19 response inquiry second phase focuses on political decisions

Tue, 2023-10-03 11:12 — mike kraft

 

Britain’s COVID-19 response inquiry enters a second phase with political decisions in the spotlight LONDON (AP) — Britain’s inquiry into the response to the coronavirus pandemic and its impact on the nation entered its second phase Tuesday, with political decision-making around major developments… PAN PYLAS, Associated Press WWTI - InformNNY.com

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Paxlovid cuts hospitalization, death only in COVID patients with weak immune systems -- Canadian study

Tue, 2023-10-03 10:44 — mike kraft

 

Study: Paxlovid cuts hospitalization, death only in at-risk COVID patients with weak immune systems seb_ra / iStock CIDRAP

...in JAMA Network Open, an observational Canadian study ties the antiviral drug combo nirmatrelvir-ritonavir (Paxlovid) to a lower risk of hospitalization or death only in very high-risk COVID-19 patients with weakened immune systems.

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WHO authorizes a second malaria vaccine. Experts warn it’s not enough to stop the disease spreading

Tue, 2023-10-03 10:24 — mike kraft
UN authorizes a second malaria vaccine. Experts warn it's not enough to stop the disease spreading The World Health Organization has authorized a second malaria vaccine in a decision that could offer countries a cheaper and a more readily available option than the world’s first shot against the parasitic disease. AP News

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Analysis: Impact of Misinformation, and Mistrust on Use of Ivermectin and Hydroxychloroquine for COVID-19

Mon, 2023-10-02 12:14 — mike kraft
Misinformation, Trust, and Use of Ivermectin and Hydroxychloroquine for COVID-19 This survey study examines the association between non–evidence-based treatment for COVID-19 and endorsement of misinformation and trust in institutions among US residents with prior COVID-19 infection. Roy H
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Sepsis associated with COVID-19 infections higher among adults than previously realized-study

Mon, 2023-10-02 10:28 — mike kraft
Sepsis associated with COVID-19 infections more common than thought Overall, SARS-CoV-2–associated sepsis was present in 28.2% of patients admitted with SARS-CoV-2. CIDRAP

...in JAMA Network Open, researchers provide new evidence that the prevalence of SARS-CoV-2–associated sepsis among hospitalized adults is higher than previously thought, but deaths from the condition became less frequent as the pandemic progressed.

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U.S. Covid markers decline overall with hospitalizations down but deaths up in some states; WHO also reports declines

Mon, 2023-10-02 10:09 — mike kraft

US COVID markers show more declines

Most of the measures the Centers for Disease Control and Prevention (CDC) uses to track COVID-19 activity declined last week, except for deaths, which are often a lagging indicator, according to the group's latest data updates. The levels reflect a recent drop in COVID activity, following several weeks of a slow summer rise from very low levels.

...the World Health Organization (WHO) posted its latest monthly update, which it cautions is based on limited data, with cases and deaths reported from only 96 countries and even fewer countries regularly reporting hospitalizations and intensive care unit (ICU) admissions. It also said its assessments are limited by reduced testing and delays in reporting.

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